By Howard Maibach, Golara Honari
Applied Dermatotoxicology: medical Aspects presents concise, systematic, and state of the art details at the toxicological results of gear on pores and skin, and up to date advances in dermal toxicity trying out.
This e-book in particular addresses the medical displays borne out of publicity to various chemical substances. It starts with an summary of dermis biology to supply toxicologists with a easy figuring out of its anatomy and body structure. subsequent it offers a number of dermatotoxicological results, besides on the poisonous brokers that reason them, with colour images to demonstrate those results.
Applied Dermatotoxicology: medical Aspects is a vital reference for toxicologists in undefined, and for these doctors who come across circumstances of dermal publicity to poisonous brokers.
- A concise, but inclusive evaluate of results of chemical exposure
- Includes heritage on uncomplicated dermis biology
- Provides very important medical reference for toxicologists in non-clinical settings
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Extra resources for Applied Dermatotoxicology. Clinical Aspects
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Highest concentration should be physiologic, not exceeding 1000 µg/ mL and osmolality should not exceed 10 mmolar. A geometric dilution series of eight test substance concentrations including a negative control or solvent are added to wells for 1 h (37 C, 5% CO2 in air). 52 • • • • • • Applied Dermatotoxicology A known phototoxic chemical (Chlorpromazine) is added to each well as a positive control. One set of wells is exposed to 5 J/cm2 in the UVA range for 50 min, while the other set is kept in dark.
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